Anti-Pollution Matrix EN – Categories of Active Ingredients and Product Classes – Repair – Products with anti-inflammatory effect

Anti-Pollution Matrix

Products with anti-inflammatory effect

Anti-Pollution Matrix > Categories of Active Ingredients and Product Classes > Repair
> Products with anti-inflammatory effect


Particulate matter, pollen and sunlight induce the secretion of pro-inflammatory cytokines such as TNF-α, IL-1α and IL-8, leading to increased skin inflammation, redness and aging.


Possible approaches

Incorporation of cosmetic anti-inflammatory agents into formulations unless dermatological pharmaceutical treatments are required.


Product categories

Face & skin care products (e.g. creams, serums, ointments)


Examples of ingredients

Cosmetic ingredients known to modulate inflammation.

  • Plant extracts for inflammation/irritation triggered by oxidative stress.
  • High molecular weight molecules as film formers (e.g., polysaccharides)
  • Chelating agents (for inflammation triggered by heavy metals)
  • UVA and UVB filters for sun-induced inflammation/irritation
  • Other specific actives such as vitamins (e.g. provitamin B5) and minerals (e.g. zinc)

As efficacy is generally concentration- and matrix-dependent, proofs of efficacy are required.


Examples of claims
  • provides protection against pollution and stress in urban environments
  • helps reduce inflammation triggered by pollutants
  • improves texture and smoothness of stressed skin
  • can relieve/soothe inflammation caused by pollutants


Examples of evidence of efficacy / Methods

Imaging procedures and color measurement methods that can be used to detect skin redness or its disappearance.

Example: chromameter, high-resolution color cameras such as VISIA®, Colorface® and the like.

Non-invasive methods such as adhesive tear (tape strip), or invasive methods such as suction blisters (suction blister) and biopsies, which can detect an increase or decrease in inflammatory markers such as cytokines.


  • Velasco et al, 2018, Active ingredients, mechanisms of action and efficacy tests of antipollution cosmetic and personal care products. Brazilian Journal of Pharmaceutical Sciences,54 (Special): e01003,
  • Juliano et al., 2018, Cosmetic Functional Ingredients from Botanical Sources for Anti-Pollution Skincare Products Cosmetics, 5, 19;
  • Krutmann et al., 2014, Pollution and skin: from epidemiological and mechanistic studies to clinical implications. J Dermatol Sci. 76(3):163-8, DOI: 10.1016/j.jdermsci.2014.08.008